UCSF Health medical specialists have reviewed this information. It is for educational purposes only and is not intended to replace the advice of your doctor or other health care provider. We encourage you to discuss any questions or concerns you may have with your provider. Anal fissures are cracks or tears in the skin around the anus, causing burning and sharp pain when you have a bowel movement.
Absorption kinetics of rectally and orally administered ibuprofen.
After Anal and Rectal Surgery | Patient Education | UCSF Health
This leaflet gives tips about how to give rectal medicines suppositories and enemas to children. This leaflet has been written specifically about the use of medicines in children. Please read this leaflet carefully. Keep it somewhere safe so that you can read it again. Rectal medicines are administered given through the anus into the rectum back passage, or bottom. They must not be taken by mouth.
6.4 Administering Medications Rectally and Vaginally
View Full Version : Headache relief taken anally. Send questions for Cecil Adams to: cecil straightdope. Your direct line to thousands of the smartest, hippest people on the planet, plus a few total dipsticks. As I was swallowing some acetaminophen, I got to wondering, would this pill work equally well, if taken anally?
The bioavailability of rectally administered sodium ibuprofen solution and aluminum ibuprofen suspension was determined in eight normal subjects relative to the same treatments administered orally. The results indicate that the suspension was less bioavailable than the solution irrespective of the route of administration. Although not bioequivalent, rectally administered ibuprofen solution compared favourably with orally administered ibuprofen solution. The mean AUC and Cmax from rectal administration were 87 per cent and 62 per cent of the corresponding values achieved after oral administration.